Organic Acid Quantitation (Methylmalonic Acid)

Also known as: organic acid quantitation – MMA, urinary organic acids: isolation and quantitation, metabolic analysis profile.

What is organic acid quantitation - methylmalonic acid?

Organic acid quantitation - methylmalonic acid is a test that can help diagnose a rare metabolic genetic disorder known as methylmalonic acidemia (MMA). The test measures the levels of an organic acid known as methylmalonic acid in the urine. High levels are usually a sign of methylmalonic acidemia.

What happens during the procedure?

A sample of urine is required for organic acid quantitation. The sample is then sent to a laboratory for further testing and analysis.

Is any special preparation needed?

The patient may need to fast for several hours before giving a urine sample.

What are the risk factors?

There are no risk factors related to this test.


Reviewed by: Sajel L Kana, MD

This page was last updated on: September 16, 2025 12:47 PM

Genetic and Metabolic Disorders

Certain pediatric health conditions have a root cause in genetics

Learn More
Check Your Symptoms
Use the symptom checker tool to check how serious your symptoms are, if a healthcare visit is needed, and what steps you can take to relieve your symptoms at home.

Learn more about