Organic Acid Quantitation (Succinylacetone)

Also known as: urinary organic acids: isolation and quantitation, metabolic analysis profile.

What is organic acid quantitation - succinylacetone?

Organic acid quantitation - succinylacetone is a test that can help diagnose a rare genetic disorders known as tyrosinemia type 1. The test measures the levels of an organic acid known as succinylacetone in the urine. High levels of urine succinylacetone are usually a sign of tyrosinemia type 1.

What happens during the procedure?

A sample of urine is required for organic acid quantitation. The sample is then sent to a laboratory for further testing and analysis.

Is any special preparation needed?

The patient may need to fast for several hours before giving a urine sample.

What are the risk factors?

There are no risk factors related to this test.

Reviewed by: Sajel L Kana, MD

This page was last updated on: September 16, 2025 12:47 PM

Genetic and Metabolic Disorders

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Organic Acid Quantitation

Organic acid quantitation is a test that can help identify a number of genetic disorders that impact metabolism.

Biochemical Genetic Test: Urine Organic Acids

Metabolism is the sum of the chemical processes whereby the body builds new molecules and breaks down others to get rid of waste products and produce energy.