Van der Woude Syndrome
Also known as: VDWS.
What is Van der Woude syndrome?
Van der Woude syndrome is a genetic disorder that affects the mouth and face. The most common symptoms are cleft lip, cleft palate, depressions (pits) or extra tissue on the lower lip and missing teeth on occasion.
What causes Van der Woude syndrome?
Van der Woude syndrome occurs due to a genetic mutation, and it can be passed along from an affected person to their children. The condition can also occur for the first time in a person.
What are the symptoms of Van der Woude syndrome?
The facial differences are the primary symptoms of Van der Woude syndrome. Children with the condition may have developmental delays or learning disabilities, as well.
What are Van der Woude syndrome care options?
Various surgical procedures can be used to correct the facial differences that arise as part of Van der Woude syndrome.
Reviewed by: Mislen S Bauer, MD
This page was last updated on: 9/16/2025 12:31:04 PM
Craniofacial Center
The Craniofacial Center at Nicklaus Children's Hospital is one of Florida's leading specialty centers offering comprehensive management for infants, children, and young adults with an array of craniofacial differences.
Learn MoreUse the symptom checker tool to check how serious your symptoms are, if a healthcare visit is needed, and what steps you can take to relieve your symptoms at home.