Syndrome of Inappropriate Antidiuretic Hormone Secretion

Also known as: SIADH, ectopic ADH secretion.

What is syndrome of inappropriate antidiuretic hormone secretion?

Antidiuretic hormone, or ADH, is a substance produced by the pituitary that controls how much water the body excretes in the urine. When syndrome of inappropriate antidiuretic hormone secretion (SIADH) is present, the body retains too much water.

What causes syndrome of inappropriate antidiuretic hormone secretion?

Some medical conditions including infections, certain medications, cancer, and surgery can all play a role in causing syndrome of inappropriate antidiuretic hormone secretion.

What are the symptoms of syndrome of inappropriate antidiuretic hormone secretion?

In some cases, syndrome of inappropriate antidiuretic hormone secretion may not cause any symptoms. Other times, headache, balance problems, mental changes and nausea and vomiting can occur.

What are syndrome of inappropriate antidiuretic hormone secretion care options?

Limiting fluid intake is the first-line treatment for syndrome of inappropriate antidiuretic hormone secretion. Depending on the cause, adding sodium, changing medication, taking other medications may be recommended to treat the problem.

Reviewed by: Adriana Alejandra Carrillo Iregui, MD

This page was last updated on: 9/16/2025 12:32:48 PM