McCune-Albright Syndrome

Also known as: MAS.

What is McCune-Albright syndrome?

McCune-Albright syndrome is a genetic disorder that impacts the bones, skin and endocrine system. The main characteristic is the development of scar-like tissue in the bones due to a condition called polyostotic fibrous dysplasia.

What causes McCune-Albright syndrome?

McCune-Albright syndrome is caused by genetic mutations. It is not passed down from parents to children but instead occurs randomly.

What are the symptoms of McCune-Albright syndrome?

The bone scarring that occurs with McCune-Albright syndrome often leads to uneven growth of bones, deformities and fractures. Problems with the face and a curved spine (scoliosis) are common. Skin patches called café-au-lait spots are common as are other symptoms related to the endocrine system disturbance such as rapid heart rate, high blood pressure, sweating and other symptoms.

What are McCune-Albright syndrome care options?

There is no cure for McCune-Albright syndrome. Treatment is focused on preventing problems or managing them as they occur through medications and surgery.