McCune-Albright Syndrome
Also known as: MAS.
What is McCune-Albright syndrome?
McCune-Albright syndrome is a genetic disorder that impacts the bones, skin and endocrine system. The main characteristic is the development of scar-like tissue in the bones due to a condition called polyostotic fibrous dysplasia.
What causes McCune-Albright syndrome?
McCune-Albright syndrome is caused by genetic mutations. It is not passed down from parents to children but instead occurs randomly.
What are the symptoms of McCune-Albright syndrome?
The bone scarring that occurs with McCune-Albright syndrome often leads to uneven growth of bones, deformities and fractures. Problems with the face and a curved spine (scoliosis) are common. Skin patches called café-au-lait spots are common as are other symptoms related to the endocrine system disturbance such as rapid heart rate, high blood pressure, sweating and other symptoms.
What are McCune-Albright syndrome care options?
There is no cure for McCune-Albright syndrome. Treatment is focused on preventing problems or managing them as they occur through medications and surgery.
This page was last updated on: 9/16/2025 12:35:08 PM
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