What is Beckwith-Wiedemann Syndrome?

Beckwith-Wiedemann syndrome, or BWS, is a genetic condition caused by abnormal gene regulation. It can cause premature birth, low blood sugar, abdominal problems, and macroglossia (enlarged tongue). Approximately 300 children per year are born with Beckwith-Wiedemann syndrome and while most cases are sporadic, some may be hereditary depending on the underlying cause.

Center for Beckwith-Wiedemann Syndrome

The Center for Beckwith-Wiedemann Syndrome at Nicklaus Children's Hospital is one of the leading programs in the world for BWS treatment, continuously helping children with BWS go on to live healthy, normal lives. We offer a multidisciplinary approach to care that addresses the full scope of needs for patients with this congenital disorder. The center is also one of the few in the nation with long-standing interest and experience in caring for children with BWS.

Treatments and Procedures

At Nicklaus Children's Hospital, we treat both Beckwith-Wiedemann syndrome and Macroglossia. Our pediatric care services include:

• Macroglossia Surgery
• Prenatal Beckwith-Wiedemann syndrome diagnosis
• Surgical treatment of macroglossia (enlarged tongue)
• Treatment and therapy for BWS symptoms
• Ongoing screening protocols